holoprosencephaly

== English == === Etymology === From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. By surface analysis, holo- +‎ pro- +‎ -s- +‎ encephal- +‎ -y. === Pronunciation === Rhymes: -ɛfəli === Noun === holoprosencephaly (countable and uncountable, plural holoprosencephalies) (teratology) A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be. ==== Synonyms ==== HPE (abbreviation) ==== Hyponyms ==== cyclopia ==== Coordinate terms ==== Classifications of holoprosencephaly alobar semilobar lobar Associated facial deformities premaxillary agenesis cyclopia ethmocephaly cebocephaly ==== Derived terms ==== ==== Related terms ==== prosencephalon encephalon ==== Translations ==== === References === NINDS Holoprosencephaly Information Page at the (U.S.) National Institutes of Health