general paresis of the insane

== English == === Alternative forms === general paresis (short form), GPI (initialism) === Noun === general paresis of the insane (uncountable) (pathology) A neuropsychiatric disorder caused by late-stage syphilis, and characterized by fatigue, headaches, insomnia, personality changes, delusions, etc. [from 19th c.] ==== Synonyms ==== (neuropsychiatric disorder caused by syphilis): general paralysis of the insane, paralytic dementia ==== Translations ==== === Further reading === general paresis of the insane on Wikipedia.Wikipedia